Mackenzies liv är inte detsamma sedan bästa vännen Amy dräptes av en vit varulf. Nu jagas hon av vännen i sinna drömmar medan en extremistgrupp kommit till stan för att jaga ned dråparen. Hon bestämmer sig för att själv finna denne.
   Mackenzie and Amy were best friends. Until Amy was brutally murdered. Since then, Mac's life has been turned upside down. She is being haunted by Amy in her dreams, and an extremist group called the Trackers has come to Mac's hometown of Hemlock to hunt down Amy's Killer: A white werewolf. Lupine Syndrome - the werewolf virus - is on the rise across the country. Many of the infected try to hide their symptoms, but bloodlust is not easy to control and the Trackers are determined to stop those with Lupine Syndrome, at any cost. Unwilling to work with the brutal Trackers, but desperately wanting to put an end to her nightmares, Mac decides to investigate Amy's murder herself. But the deeper she delves into the mystery behind Amy's death, the more secrets she discovers lurking in the shadows of Hemlock. Secrets that should have been left untold. Secrets that will change her life forever.